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What is Artesunate 180mg used for?
This is a higher dose medicine for treating critical malaria cases for adult patients, usually those with higher body weight. Because of the dosage strength, the medicine rapidly reaches concentration levels in the bloodstream to prevent life-threatening consequences.
How does Artesunate 180mg work?
As a schizonticide, Artesunate 180mg gets metabolized to dihydroartemisinin and reacts to the iron in the heme of the parasite by releasing free radicals. The membranes and the proteins of the bacteria get damaged, destroying the parasite in their multiplication stage. Thus, the medication causes clearance of the infection from the system.
What are the Artesunate 180mg ingredients and available forms?
Artesunate is the active component, available in sterile powder state, ready to be reconstituted in sodium bicarbonate and then in saline to administer intramuscularly or intravenously.
How long does Artesunate 180mg take to act?
The peak plasma levels occur instantly after administration of the injection. It may take 6 to 12 hours for parasite reduction to begin, with rapid lowering of the parasite’s existence in the first 24 hours.
How long does the treatment with Artesunate 180mg last?
The injection is delivered three times in the first 24 hours, followed by three doses as indicated by the healthcare provider. After the person can tolerate oral dosage, a full three days of course is advisable with oral Artemisinin-based Combination Therapy (ACT) to clear the infection.
What are the Artesunate 180mg benefits?
The primary benefit is usefulness in severe malaria cases along with rapid onset restrict parasite multiplication in weighty adults. It does away with the need to multiple doses of lower dosages, and is ideal for emergency situations.
What is the Artesunate 180mg dosage and administration?
The general dose is calculated according to the person’s weight i.e. 2.4 mg of the medicine/kg. The first dose is taken at 0 hours, then the second after 12 hours, and the last dose at 24 hours. After this, a daily dose is required as advised by the doctor combined with ACT oral course.
What are the Artesunate 180mg side effects?
Common side effects are nausea, vomiting, abdominal pain, diarrhea, and dizziness. In rare cases, red blood cells break down 1 to 3 weeks after treatment. In rare cases, some people may encounter low count for white blood count, while others may experience higher levels of liver enzymes.
What are precautions and contraindications of Artesunate 180mg?
If someone has an allergy to this medicine’s ingredients, then they must seek an alternate treatment, that is even true if a woman is in her first trimester but contracted malaria. Never use this medication for long-term treatment as a solo agent. It should always be taken with another antimalaria to prevent relapse.
