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What is Artesunate 120mg used for?
This medicine treats severe cases of malaria caused from Plasmodium falciparum. It is efficient for adults and children. It is known for rapid action, especially useful in hospital settings where patients in critical condition cannot take oral meds and need something dependable to save them from life-threatening consequences.
How does Artesunate 120mg work?
The free radicals released from this medicine react to the parasite’s iron in the heme, resulting in destruction of the pathogen by damaging the membranes and proteins of the same. It is helpful in reducing the parasite count, deterring their multiplication in early stages of their life cycle.
What are the Artesunate 120mg ingredients and available forms?
The active component in this 120mg medicine is artesunate. It is a water-soluble hemisuccinate derivative of dihydroartemisinin, provided as a sterile powder. Once reconstituted in sodium bicarbonate or sodium chloride diluent, this medicine is injected intramuscularly or intravenously.
How long does Artesunate 120mg take to act?
The medicine is quick to act with peak plasma levels reached in a few minutes of intravenous administration. Significant reduction of parasite count is expected along with lowered fever, in 12 to 24 hours of beginning the treatment.
How long does the treatment with Artesunate 120mg last?
One dose is taken every 0, 12, and 24 hours on the first day. After this, doctors usually recommend an oral Artemisinin-based Combination Therapy (ACT) for the next 3 days to clear the parasite remains from the bloodstream.
What are the Artesunate 120mg benefits?
The primary function of the medicine is to clear parasites from the patient’s bloodstream, improving survival changes and impact on the brain. It is also beneficial compared to older medications such as quinine. It also treats critically ill patients, with a lower risk of cardiac arrhythmias and hypoglycemia.
What is the Artesunate 120mg dosage and administration?
The dose differs as per the weight. The standard dose goes by 2.4 mg/kg body weight taken at 0, 12, and 24 hours, and then followed by once per day dosage. The medicine is injected by dilating with saline after a bicarbonate buffer. The treatment is switched to oral medicine and ACT full course once the patient becomes better.
What are the Artesunate 120mg side effects?
Some common side effects are abdominal pain, nausea, vomiting, and dizziness. A sudden drop in hemoglobin may happen in some people after weeks of the treatment. In rare cases, the medication may result in anaphylaxis or allergic reactions.
What are precautions and contraindications of Artesunate 120mg?
Keeping a check on blood cell count regularly is advised after recovery. Contraindication is allergy to the medicine’s ingredients. It is advisable to avoid this agent in the first trimester of pregnancy until asked by a doctor and under medical supervision. It should not be taken solely but included as a part of combined therapy with ACT course.
