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What is Imatinib Mesylate used for?
Imatinib Mesylate treats several severe conditions such as Philadelphia chromosome-positive acute lymphoblastic leukemia, gastrointestinal stromal tumors (GISTs), chronic myelogenous leukemia (CML), rare tumors, and other cancers related to blood. It is useful for health issues such as myelodysplastic syndromes and systemic mastocytosis.
How does Imatinib Mesylate work?
This medicine may inhibit some types of tyrosine kinase enzymes. Such as PDGF receptors, BCR-ABL, and others responsible for cancer cell growth. Thus, Imatinib Mesylate blocks these enzymes to cause apoptosis in cancer cells. This action mechanism slows down the progression of cancer cells, and slows down the advancement of the disease.
What are the Imatinib Mesylate ingredients and available forms?
The active ingredient is imatinib mesylate. The medicine is available as an oral solution or tablet. The inactive ingredients could include talc, hydroxypropyl methylcellulose, crospovidone, colorants such as iron oxides, colloidal silicon dioxide, magnesium stearate, etc.
How long does Imatinib Mesylate take to act?
The medication effect may differ in effects and time of action depending on the severity of condition. In some cases, especially leukemia, it may take several weeks and months to slow down the cancer cell growth and spread of the disease. Consistent use is required for ongoing benefits.
How long does the treatment with Imatinib Mesylate last?
The duration of treatment for chronic problems like CML and others is for lifelong or long-term. Duration up to 12 to 36 months may be taken by the medicine for significant improvement to prevent relapse.
What are the Imatinib Mesylate benefits?
The benefits of the medicine include management of GISTs and CML, and other conditions. It reduces the symptoms and has lower side effects compared to traditional chemotherapy. It also helps the patient lead a better life with faster action.
What is the Imatinib Mesylate dosage and administration?
The dose for adults is one a day between 400mg and 600mg. In some cases, the dose is between 400mg and 800mg two times a day. You must take the medicine with a meal. Take the tablet as a while with water to reduce side effects of gastrointestinal nature. Doses for children will depend on age, severity of symptoms, body surface area, etc.
What are the Imatinib Mesylate side effects?
Common side effects include edema, nausea, fatigue, muscle cramps, rash, fever, diarrhea, and gastrointestinal problems. Serious effects are rare but may include liver toxicity, fluid retention, blood cell abnormalities, and increased risk of infection.
What are Imatinib Mesylate's precautions and contraindications?
Dose must be monitored in case of use in people with fluid retention, liver function problems, blood cell counts, and medicine interactions. Those with allergy to medicine contents must seek an alternative. Caution should be taken for people with heart conditions and liver disorders.
