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What is Gabapentin Enacarbil used for?
This medicine treats moderate to severe RLS (Restless Legs Syndrome) and postherpetic neuralgia. It is useful to give relief against shingles-related nerve pain and uncomfortable leg sensations.
How does Gabapentin Enacarbil work?
Gabapentin Enacarbil binds to voltage-dependent calcium channels and gets converted to gabapentin after being absorbed in the system. It calms down agitated nerves in the body by reducing excitatory neurotransmitter release.
What are the Gabapentin Enacarbil ingredients and available forms?
The active ingredient is gabapentin enacarbil. The inactive ingredients are dibasic calcium phosphate dihydrate, glyceryl dibehenate, magnesium stearate, silicon dioxide, and talc. It comes in the form of extended-release oral tablets and the common dosage strength is 600mg.
How long does Gabapentin Enacarbil take to act?
Improvement in RLS symptoms is seen as soon as 7 days of starting the dosage. The best effect is seen after 2 weeks of dosing.
How long does the treatment with Gabapentin Enacarbil last?
The duration of treatment varies from a person to another based on the severity of the condition. For RLS, the treatment is ongoing for the long-term. The treatment may extend to 52 weeks depending on evaluation by a healthcare professional.
What are the Gabapentin Enacarbil benefits?
It combats symptoms related to sleep disturbance and leg discomfort caused from Restless Legs Syndrome. It is also helpful to reduce nerve pain. It is available as extended-release formulation for better impact.
What is the Gabapentin Enacarbil dosage and administration?
The usual dose is 600mg for adults with RLS. The medicine is taken once daily after food in the evening. The dose strength is the same, taken once daily for postherpetic neuralgia. Thereafter, the dose could be increased to twice daily. Adjustment in dose is done by the doctor by noticing the treatment’s progress.
What are the Gabapentin Enacarbil side effects?
Common side effects include dizziness, somnolence (sleepiness), ataxia (coordination issues), fatigue, and peripheral edema. Serious effects are suicidal thinking, jaundice, unusual tiredness, or allergic reactions.​
What are Gabapentin Enacarbil's precautions and contraindications?
Caution is advised in people with renal problems, those with suicidal thoughts, and people using CNS depressants. Contraindications are alcohol and hypersensitivity to gabapentin enacarbil or gabapentin.