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What is Calcifediol used for?
This medicine is used in adults with chronic kidney disease, treating secondary hyperparathyroidism. It is also taken to manage refractory rickets, osteoporosis, and vitamin D deficiency. It is beneficial for people with these complaints and with malabsorption problems as well.
How does Calcifediol work?
As a vitamin D3 analog, Calcifediol gets turned into Calcitriol in the kidney. This becomes vitamin D in its active form. Thus, Calcitriol manages levels of phosphate and calcium by increasing their absorption in the intestines, reducing production of parathyroid hormone, and stabilizing skeletal calcium, and as a result causing calcium homeostasis.
What are the Calcifediol ingredients and available forms?
The primary ingredient in this medicine is 25-hydroxyvitamin D3, or Calcifediol. It is available as softgel capsules or oral extended-release capsules. Inactive ingredients may include stabilizers, fillers, coloring agents, etc.
How long does Calcifediol take to act?
Calcifediol starts with its positive effects within a few days from the administration. It helps increase serum 25(OH)D levels. It strives to elevate vitamin D levels within 4 weeks of starting the treatment.
How long does the treatment with Calcifediol last?
The treatment time may differ from one person to another, lasting for several weeks or months. Monitoring calcium and vitamin D levels, and dose adjustment in people with kidney disease, and other factors decide how long the treatment will go on.
What are the Calcifediol benefits?
This medicine helps overcome problems absorbing calcium and vitamin D deficiency. It also eases management of osteoporosis, osteomalacia, and other bone problems, along with secondary hyperparathyroidism. It is also essential to correct kidney disease and malabsorption. It also has a rapid onset compared to cholecalciferol.
What is the Calcifediol dosage and administration?
The dose may vary between 10-25mcg daily for vitamin D deficiency. Take one capsule daily orally before bedtime. The dosing strength may depend on the level of parathyroid hormone or serum calcium in the system.
What are the Calcifediol side effects?
Side effects can include hypercalcemia, nausea, vomiting, constipation, headache, fatigue, muscle weakness, etc. It is important to monitor the effects when the medicine is taken for long-term.
What are Calcifediol's precautions and contraindications?
This medicine is contraindicated for people with vitamin D toxicity, hypersensitivity to Calcifediol, or with hypercalcemia. Taking note of vitamin D and calcium levels is advisable to check the progress of treatment. Caution is advised in patients with granulomatous disease, sarcoidosis, or kidney stones.
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