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What is Quazepam used for?
This medicine treats early morning arousal, difficulties with sleep, insomnia, and awaking regularly during sleep time. It is useful for adults but meant for short-term use such as for 7 to 10 days. However, it is not a treatment for chronic insomnia. It can be used to relieve tension-induced sleep issues before surgery as a premedication.
How does Quazepam work?
As a benzodiazepine, Quazepam selectively targets alpha-1 subunits by enhancing GABA at GABA_A receptors' benzodiazepine site. The action mechanism hyperpolarizes neurons by increasing chloride influx. As a result, the medicine produces hypnotic effects. It helps achieve restful sleep and improve sleep schedule adherence.
What are the Quazepam ingredients and available forms?
The active ingredient is quazepam, while the inactive ones include cellulose, magnesium stearate, and lactose. It is available as an oral tablet of 7.5mg to 15mg and more, depending on the manufacturer. You must take the medicine usually at bedtime.
How long does Quazepam take to act?
It can take 30 to 60 minutes for the medicine to start working. Thanks to GABA modulation and quick absorption in the system, the peak effects are noticed in 2 hours. However, for complete hypnotic action after the first night, it can give positive results with maintenance dose, over the next few days.
How long does the treatment with Quazepam last?
This medicine is for short-term administration, maximum for 7 to 10 days only to avoid dependance. If the dose extends under medical supervision, the medicine is tapered off rather than stopped abruptly. One can feel the effectiveness for a longer term when they take this medicine for at least 5 nights.
What are the Quazepam benefits?
The benefit of this medicine is that it has anticonvulsant properties. It induces sleep quickly. It is better than temazepam with minimal adverse reactions such as amnesia, daytime sedation, or motor impairment, making it a safer choice if one wishes to preserve sleep architecture. It also leads to fewer awakenings, making for less disruptive sleep patterns. It is also useful as a short-term agent leading to hypnotic effects.
What is the Quazepam dosage and administration?
For adults, the tablet is taken at bedtime. The initial dose is 15mg, which may reduce to 7.5mg when it is about maintaining the sleep cycle after one to two nights of effective sleep. For elderly individuals, the initial dose could be 7.5mg, depending on the sleep condition’s severity. Remember there is no food restriction for this medicine. It is meant for short-term intake only.
What are the Quazepam side effects?
Common side effects are daytime drowsiness, dizziness, lethargy, ataxia, and dysarthria. In rare instances, this medicine can lead to confusion, memory impairment, dependence with prolonged use. When taking Quazepam, it is important to keep a check on respiratory depression with CNS depressants.
What are precautions and contraindications of Quazepam?
Contraindications are allergy to the medicine and its ingredients and acute narrow-angle glaucoma. Precautions are starting with low doses for elderly, people with depression, liver/kidney disorders, pregnancy of category X, history of substance abuse, lactation, etc. Do not take CNS depressants and alcohol if intending to take Quazepam. Also taper the dose to keep away withdrawal symptoms.