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Ketoconazole

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Ketoconazole
Yeast Infection

Ketoconazole

What is Ketoconazole used for?

This medicine is used to treat yeast and fungal infections such as histoplasmosis, candidiasis, blastomycosis, and other skin infections caused by fungus such as ringworm, athlete’s foot, and seborrheic dermatitis. It is also useful in cases other antifungal treatment and medicines are not available or people have tolerance issues with them.

How does Ketoconazole work?

Ketoconazole stops the synthesis of ergosterol. This element is otherwise important for fungal cell membranes. The medicine destroys the membrane structure causing leakage in fungal cell, preventing the growth of fungus and their spread. By inhibiting fungal cell replication and enzymes, it treats the infection.

What are the Ketoconazole ingredients and available forms?

The active ingredient is ketoconazole. The formats available are topical foams, creams, gels, oral tablets, and medicated shampoos (1% and 2%) for dermatitis treatment and scalp infections.

How long does Ketoconazole take to act?

The topical treatment shows improvement within days for the symptoms but full recovery or best benefits are observed after a few weeks of use. Oral tablets deal with systemic infections and can go on for several weeks to show reduction in infection symptoms.

How long does the treatment with Ketoconazole last?

Duration of treatment may go on for 2 to 8 weeks depending on the form of medicine used. Oral tablets are targeted to manage systemic infections, and the treatment may last longer depending on the individual’s response. However, medical supervision is advised to reduce risk of liver toxicity in case of long-term use.

What are the Ketoconazole benefits?

This medicine does not just treat systemic topical infections but several types of fungal infections. The target is to reduce symptoms such as inflammation and itching. In some cases, Ketoconazole is also taken to manage hormone-related problems due to its antiglucocorticoid and antiandrogen effects.

What is the Ketoconazole dosage and administration?

Oral tablets in the range of 200mg to 400mg are taken daily under medical supervision for severe infections. Topical forms are applied once or twice in a day for two to eight weeks, depending on the severity of the infection.

What are the Ketoconazole side effects?

Common side effects include nausea, vomiting, abdominal pain, itching, and skin irritation. In the case of oral medicine, sometimes serious effects such as adrenal insufficiency, liver toxicity, and hormonal imbalances can happen. In case of topical treatment, severe effects may include local rash or irritation.

What are Ketoconazole's precautions and contraindications?

This medicine is contraindicated in people with allergy to the medicine’s contents, with liver disease, or in pregnancy. If taking oral tablets, it is important to monitor liver function. It should not be combined with medicine interactions. Use cautiously in people with hormone or adrenal-related medical problems.

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