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What is Balsalazide used for?
Balsalazide is used to treat moderate or mildly active chronic inflammatory bowel disease, i.e., ulcerative colitis. It reduces the sores and swellings in the large intestines, and helps in the maintenance of remission and improving tolerability to the symptoms.
How does Balsalazide work?
This medicine remains inactive till it reaches the colon. The bacterial action in the colon with the medicine releases mesalamine (5-ASA), the active anti-inflammatory agent, which reduces the side effects by suppressing systemic absorption of the chemical. The process eases inflammation, ulceration, and swelling in the rectum and colon.
What are the Balsalazide ingredients and available forms?
Balsalazide contains balsalazide disodium, which is one of mesalamine. It is available as oral capsules (Colazal capsules (750 mg) and oral tablets (Giazo 1.1g).
How long does the treatment with Balsalazide last?
Treatment time in adults for ulcerative colitis is up to 8 to 12 weeks, while that for children in the age group 5 to 17 is up to 8 weeks. Do not alter the dose or abruptly stop the treatment by yourself. In maintenance therapy, long-term use of Balsalazide may occur for 12 months to 1.4 years, depending on the doctor’s recommendation.
What are the Balsalazide benefits?
The benefits of Balsalazide include local relief from symptoms in the colon and rectum, elimination of oxidative stress, reduced side effects, lower risk of relapse, faster relief, and better remission rates, and others.
What is the Balsalazide dosage and administration?
You need to take a capsule or tablet, be it in any of these forms, orally with water. If you find it difficult to swallow a capsule, you may open it and ingest.
What are the Balsalazide side effects?
The common side effects are nausea, vomiting, headache, fatigue, tiredness, abdominal pain, gas, cramping, constipation, diarrhea, joint and muscle pain, fever or flu-like symptoms, or increased sensitivity to sunlight or light.
What are Balsalazide's precautions and contraindications?
Avoid Balsalazide if you have kidney/liver disorders, an allergy to salicylates or aminosalicylates, and children under 5 years. Caution and medical supervision are advised for use in people with acute intolerance syndrome, pyloric stenosis or intestinal obstruction, women lactating or pregnant, with severe skin diseases, with risk of mesalamine-induced organ toxicity, or if it has just been six weeks after receiving the varicella virus vaccine.
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